Cognitive Impact

Clostridium Difficile Infection

Clostridium Difficile (C. Difficile) is a bacterial cause of diarrhea in hospitalized patients and in those who have been treated with prolonged antibiotics. It is characterized by watery diarrhea with dehydration and overwhelming abdominal sepsis and shock. The infection is hard to detect as it overlaps with many other causes of diarrhea and requires a high “index of suspicion” on the part of caregivers. Moreover, the bacteria that causes C. Difficile is resistant and hard to eradicate.
A Clostridium Difficile Infection (CDI) causes significant risk of morbidity and increased costs for providers and the patients suffering from the infection. In a recent study conducted by the National Heart, Lung, and Blood Institute (NHLBI), the average hospital cost for CDI per case ranges from $9,000 to $11,500 and one in 11 patients over the age of 65 will die within a month of a CDI diagnosis. The total cost of U.S. healthcare for CDIs approaches $500 Million per year. And the average increase in length of stay directly attributed the infection varies widely between 3 and 21 days.
Jvion’s Cognitive Clinical Success Machine is equipped to identify patients at risk of developing a CDI during a hospital stay. The machine incorporates the latest CDI research and clinical intelligence to pin point individuals on a risk trajectory toward a CDI while accounting for those asymptomatic patients who are nearly impossible to detect. The machine renders granular, patient-level propensity information that is customizable to a provider’s operational needs. The clinical actions enabled by the Cognitive Clinical Success Machine empower care givers with the information they need to work collaboratively across functions to lower CDI rates and losses while improving health outcomes.


  • Clin Microbiol Infect. 2012 Mar;18(3):282-9. doi: 10.1111/j.1469-0691.2011.03571.x. Epub 2011 Jun 10.
  • J Hosp Infect. 2014 Sep;88(1):12-21. doi: 10.1016/j.jhin.2014.04.011. Epub 2014 May 17
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